Angiogenesis occurs by vessel elongation in proliferative phase human endometrium
نویسندگان
چکیده
منابع مشابه
Angiogenesis occurs by vessel elongation in proliferative phase human endometrium.
BACKGROUND Angiogenesis occurs by at least three mechanisms: sprouting, intussusception and elongation. Studies to date have failed to identify the mechanisms or timing of endometrial angiogenesis during the menstrual cycle. The aim of this study was to determine if vessel elongation plays a role in human endometrial angiogenesis. METHODS Forty-nine full thickness endometrial sections from 27...
متن کاملMolecular and hormonal regulation of angiogenesis in proliferative endometrium
Angiogenesis is the process of formation of new blood vessels from the blood vessels that already exist. This process is an essential factor in each menstrual cycle. Neovascularisation or formation of new blood vessel is the process occurs often in endometrium during every menstrual cycle. Abnormal angiogenesis may have a profound effect on the pathogenesis of endometrial carcinoma and abnormal...
متن کاملThrombospondin-1, an inhibitor of angiogenesis, is regulated by progesterone in the human endometrium.
Thrombospondin-1 (TSP1), a multifunctional extracellular matrix glycoprotein, has been shown to suppress the angiogenic response in vivo and in vitro. We hypothesized that TSP1 might play a role in the inhibition of capillary morphogenesis during the endometrial cycle and examined its expression in 46 human endometrial specimens. Our results show that the expression of TSP1 in the endometrium i...
متن کاملEndometrial angiogenesis throughout the human menstrual cycle.
BACKGROUND The timing and mechanisms of new blood vessel formation in the endometrium during the menstrual cycle are still largely unknown. In the present study we used the chick embryo chorioallantoic membrane (CAM) as an in-vivo assay for angiogenesis to assess the angiogenic potential of endometrium obtained at different stages of the menstrual cycle. METHODS Endometrial fragments were exp...
متن کاملSimple hyperplasia versus proliferative endometrium: stereological study
unitermos abstract The diagnosis of some forms of hyperplastic endometrium continues to present difficulties for the practicing pathologist. One of the major problems is the lack of a standard terminology for endometrial classification. Therefore, morphometrical techniques could help the accurate diagnosis. Thirteen samples of endometrium with simple hyperplasia and thirteen samples of prolifer...
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ژورنال
عنوان ژورنال: Human Reproduction
سال: 2002
ISSN: 1460-2350
DOI: 10.1093/humrep/17.5.1199